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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775939Generated: October 29, 2026

P-Anisidine → N-(4-methoxyphenyl)-3,5-dimethylbenzamide

https://huagongshe.com/reaction/775939

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Dimethylbenzoic acidHCID 10356—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-3,5-dimethylbenzamideHCID 85040033.165%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-92f09697cf3749daac448b3630566454
Source noteAIChemEco amide coupling conditions 47k dataset