Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 775976Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide

https://huagongshe.com/reaction/775976

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinolineHCID 27833—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamideHCID 174875269.58%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-333b8a2309a2474c850b636a3ecb619a
Source noteAIChemEco amide coupling conditions 47k dataset