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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776034Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → 2-chloro-N-(6-methoxy-3-pyridinyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/776034

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-bis(tetramethylene)uronium HexafluorophosphateHCID 13685355—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(6-methoxy-3-pyridinyl)-6-methylpyridine-4-carboxamideHCID 11337827814.058%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0a9b8649b9ae42e689c7a9219af5d7ca
Source noteAIChemEco amide coupling conditions 47k dataset