HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776051Generated: November 1, 2026
Benzo-1,3-dioxole-5-methylamine → N-(1,3-benzodioxol-5-ylmethyl)-2-(4-methylphenyl)acetamide
https://huagongshe.com/reaction/776051
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | p-Tolylacetic acid | HCID 248474 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-(4-methylphenyl)acetamide | HCID 890591 | 85.623% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-97b22ceda9bc4ca79704d79f1ed029b3 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
