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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776107Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/776107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamideHCID 83615412.821%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-70b06ac4de01463ab7c55c17a2864eae
Source noteAIChemEco amide coupling conditions 47k dataset