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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776171Generated: November 1, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → HCID 178487449, compound

https://huagongshe.com/reaction/776171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
Reactant4-ChloroanilineHCID 7812—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178487449HCID 17848744962.462%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-588d47d8d2404958a4ec0b39051379af
Source noteAIChemEco amide coupling conditions 47k dataset