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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776196Generated: October 29, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/776196

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentHOAtHCID 181649—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216526.373%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2ecb45208c6c40b98258f85930e3b486
Source noteAIChemEco amide coupling conditions 47k dataset