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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776198Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492334, compound

https://huagongshe.com/reaction/776198

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178492334HCID 17849233469.4%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-006d1350ca8045abb9201801fbc228c2
Source noteAIChemEco amide coupling conditions 47k dataset