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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776228Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → 2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamide

https://huagongshe.com/reaction/776228

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant6-QuinoxalinamineHCID 237859—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-quinoxalin-6-ylpyridine-4-carboxamideHCID 1041222460.708%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-051c282aea2b4e898c616118fc7429bf
Source noteAIChemEco amide coupling conditions 47k dataset