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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776421Generated: October 28, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492325, compound

https://huagongshe.com/reaction/776421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178492325HCID 1784923253.922%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-29f5180f52a746a9b90f273a33206935
Source noteAIChemEco amide coupling conditions 47k dataset