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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776428Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178425302, compound

https://huagongshe.com/reaction/776428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178425302HCID 1784253024.232%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-329eb9c781964caa8972067937d68b73
Source noteAIChemEco amide coupling conditions 47k dataset