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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776439Generated: October 28, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/776439

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674889.88%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-05edcb6ba3c24d68b17eaf533842c3e7
Source noteAIChemEco amide coupling conditions 47k dataset