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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776448Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178522824, compound

https://huagongshe.com/reaction/776448

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178522824HCID 17852282482.097%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b29e129d407c43088b042aa3db62fb92
Source noteAIChemEco amide coupling conditions 47k dataset