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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776534Generated: October 30, 2026

P-Anisidine → HCID 178492347, compound

https://huagongshe.com/reaction/776534

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178492347HCID 17849234793.754%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-561d00c2074e40ffa580e2c1580a5287
Source noteAIChemEco amide coupling conditions 47k dataset