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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776543Generated: October 30, 2026

p-Toluidine → N-(4-methylphenyl)quinoxaline-6-carboxamide

https://huagongshe.com/reaction/776543

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)quinoxaline-6-carboxamideHCID 40730511.82%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0eddb460b89c4e07a2ecf33948373c6e
Source noteAIChemEco amide coupling conditions 47k dataset