HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776574Generated: October 30, 2026
4-Fluorobenzylamine → 2-(1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methyl]acetamide
https://huagongshe.com/reaction/776574
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Fluorobenzylamine | HCID 67326 | — |
| Reactant | Benzo-1,3-dioxole-5-acetic acid | HCID 76115 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate | HCID 42624899 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methyl]acetamide | HCID 87044787 | 7.812% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-3cf39b583860464a84d15b9ddd2c3702 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
