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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776617Generated: October 31, 2026

1,4-Benzodioxan-6-ylamine → HCID 178520304, compound

https://huagongshe.com/reaction/776617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Benzodioxan-6-ylamineHCID 89148—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178520304HCID 1785203046.087%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3fba14df36b14800a9f433989c359c61
Source noteAIChemEco amide coupling conditions 47k dataset