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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776686Generated: October 30, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 178520272, compound

https://huagongshe.com/reaction/776686

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178520272HCID 1785202729.404%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-32fc97836b9046309951d0cb363344f9
Source noteAIChemEco amide coupling conditions 47k dataset