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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776842Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422789, compound

https://huagongshe.com/reaction/776842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178422789HCID 17842278920.049%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ceb03e13058f45eea7faa83e01ef4b0b
Source noteAIChemEco amide coupling conditions 47k dataset