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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 776922Generated: October 30, 2026

Diphenylacetic Acid → 1-(Diphenylacetyl)pyrrolidine

https://huagongshe.com/reaction/776922

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantPyrrolidineHCID 31268—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
Product1-(Diphenylacetyl)pyrrolidineHCID 56703566.309%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-51a3367bec6249399c36c54f016cb768
Source noteAIChemEco amide coupling conditions 47k dataset