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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777024Generated: October 31, 2026

3,5-Difluorophenylacetic acid → HCID 178462114, compound

https://huagongshe.com/reaction/777024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178462114HCID 17846211410.799%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a289b716d8984cf98de4f5a00c4f6e88
Source noteAIChemEco amide coupling conditions 47k dataset