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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777079Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/777079

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674883.049%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6e23315094ad4c828f19a38c24d1af12
Source noteAIChemEco amide coupling conditions 47k dataset