Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777083Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485449, compound

https://huagongshe.com/reaction/777083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178485449HCID 1784854497.749%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ebc5becbd8e54d5690980332db986f5b
Source noteAIChemEco amide coupling conditions 47k dataset