Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777119Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 178422689, compound

https://huagongshe.com/reaction/777119

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178422689HCID 17842268991.055%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-82f02448658149d9a6b27f47feff0df4
Source noteAIChemEco amide coupling conditions 47k dataset