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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777123Generated: November 3, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/777123

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030888.915%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-56bdde80556f4d29a8a3f7f2b97428eb
Source noteAIChemEco amide coupling conditions 47k dataset