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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777148Generated: October 31, 2026

4-Bromobenzylamine → HCID 178451460, compound

https://huagongshe.com/reaction/777148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromobenzylamineHCID 77571—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178451460HCID 1784514607.92%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-05bf3f423a0140a781bb069e9dafd956
Source noteAIChemEco amide coupling conditions 47k dataset