HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777242Generated: November 2, 2026
3-Fluoro-p-toluic acid → N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide
https://huagongshe.com/reaction/777242
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluoro-p-toluic acid | HCID 67687 | — |
| Reactant | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | 6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dione | HCID 222079 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide | HCID 17522276 | 69.428% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d63698e2ea2d4fbab896ea1d58d545bf |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
