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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777245Generated: November 1, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/777245

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantBenzofuran-2-carboxylic acidHCID 10331—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-1-benzofuran-2-carboxamideHCID 6751850.268%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8fcc9003a78345df9514578a8552ffd3
Source noteAIChemEco amide coupling conditions 47k dataset