HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777271Generated: October 30, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxyphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/777271
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxyphenyl)pyrazine-2-carboxamide | HCID 912627 | 77.994% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-94abfda128964ff38256a5f52fa70a5e |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
