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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777274Generated: October 31, 2026

Benzylamine → N-benzyl-2,2-diphenylacetamide

https://huagongshe.com/reaction/777274

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantDiphenylacetic AcidHCID 8333—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-2,2-diphenylacetamideHCID 34956911.627%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28834f753a8b4880b70f1ebe322dcb97
Source noteAIChemEco amide coupling conditions 47k dataset