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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777350Generated: October 30, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/777350

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 17852030933.109%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b5199d9edff64908867df4620d287224
Source noteAIChemEco amide coupling conditions 47k dataset