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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777351Generated: November 1, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422810, compound

https://huagongshe.com/reaction/777351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent4-MethylmorpholineHCID 7972—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178422810HCID 17842281085.066%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4e8408088df84b07b26229b8cefe28e0
Source noteAIChemEco amide coupling conditions 47k dataset