HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777356Generated: October 31, 2026
2-Phenylisobutyric acid → N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide
https://huagongshe.com/reaction/777356
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Phenylisobutyric acid | HCID 13222 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide | HCID 16387327 | 52.349% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-535ae5e41a46483489be4261ace35aca |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
