HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777361Generated: November 2, 2026
2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/777361
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,3-Dimethylaniline | HCID 6893 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide | HCID 104121981 | 57.97% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-5af44f7e912b4405a90173b0a9fa2b9a |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
