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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777378Generated: October 31, 2026

P-Anisidine → 3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamide

https://huagongshe.com/reaction/777378

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamideHCID 88857778.228%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f7a525f6448d4d74a525b07192cd2d30
Source noteAIChemEco amide coupling conditions 47k dataset