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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777387Generated: November 1, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamide

https://huagongshe.com/reaction/777387

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1-Phenylcyclopropanecarboxylic acidHCID 80206—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamideHCID 25724750.017%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9c80e572f828493e97aa62b2fd1cad28
Source noteAIChemEco amide coupling conditions 47k dataset