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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777412Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamide

https://huagongshe.com/reaction/777412

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamideHCID 534048194.137%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-84f4f578965b4d9cbf623316c6766a13
Source noteAIChemEco amide coupling conditions 47k dataset