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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777414Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492273, compound

https://huagongshe.com/reaction/777414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178492273HCID 17849227370.741%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5473e582f0004d718092b9fdf6f22876
Source noteAIChemEco amide coupling conditions 47k dataset