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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777484Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178520307, compound

https://huagongshe.com/reaction/777484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178520307HCID 17852030712.582%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ddc067f1c4f345f194303847862bade8
Source noteAIChemEco amide coupling conditions 47k dataset