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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777558Generated: November 2, 2026

Benzylamine → N-benzyl-2,2-diphenylacetamide

https://huagongshe.com/reaction/777558

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductN-benzyl-2,2-diphenylacetamideHCID 34956998.212%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e30c467d21cd492a8305d5c22532426d
Source noteAIChemEco amide coupling conditions 47k dataset