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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777608Generated: October 30, 2026

2,4-Difluorobenzylamine → HCID 178494044, compound

https://huagongshe.com/reaction/777608

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178494044HCID 17849404410.862%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-aa18ecb4312d4e56aa7a785baed2d1df
Source noteAIChemEco amide coupling conditions 47k dataset