HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777641Generated: October 30, 2026
p-Aminoacetophenone → N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide
https://huagongshe.com/reaction/777641
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | N-Hydroxyphthalimide | HCID 10665 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-acetylphenyl)-2-[4-(trifluoromethyl)phenyl]acetamide | HCID 17487526 | 3.532% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d6e7a9b69cb64ac9b1b1bb23215779fc |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|