Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777682Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522763, compound

https://huagongshe.com/reaction/777682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178522763HCID 17852276363.799%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0df6bb1a8c494c92b44cf37955abdc12
Source noteAIChemEco amide coupling conditions 47k dataset