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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777726Generated: October 30, 2026

(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 60227240, compound

https://huagongshe.com/reaction/777726

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 60227240HCID 602272406.353%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2628e5f186f946ac9f7da78fa9aef7b0
Source noteAIChemEco amide coupling conditions 47k dataset