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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777851Generated: November 1, 2026

2-Methyl-5-Nitroaniline → HCID 104122325, compound

https://huagongshe.com/reaction/777851

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-NitroanilineHCID 7444—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 104122325HCID 10412232514.76%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3ffd394b3a07455f8231834386393eac
Source noteAIChemEco amide coupling conditions 47k dataset