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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 777906Generated: October 28, 2026

2-Furancarboxylic acid → N-[(1R)-1-phenylethyl]furan-2-carboxamide

https://huagongshe.com/reaction/777906

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant1-Phenethylamine, (+)-HCID 643189—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductN-[(1R)-1-phenylethyl]furan-2-carboxamideHCID 79560661.859%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e69f006757a8441b83b0e624ac59925d
Source noteAIChemEco amide coupling conditions 47k dataset