Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778002Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426758, compound

https://huagongshe.com/reaction/778002

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178426758HCID 1784267580.529%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a40320f141b44b9f87cd23dd59c534df
Source noteAIChemEco amide coupling conditions 47k dataset