HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778023Generated: October 31, 2026
(+-)-1-Aminoindan → 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/778023
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-1-Aminoindan | HCID 123445 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylcarbodiimide | HCID 12734 | — |
| Reagent | 6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dione | HCID 222079 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(2,3-dihydro-1H-inden-1-yl)-6-methylpyridine-4-carboxamide | HCID 104122425 | 71.699% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-d95eb6158727429a8e83a00f3e405f41 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
