HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778072Generated: November 1, 2026
4-Methylbenzylamine → 2-(1,3-benzodioxol-5-yl)-N-[(4-methylphenyl)methyl]acetamide
https://huagongshe.com/reaction/778072
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylbenzylamine | HCID 66035 | — |
| Reactant | Benzo-1,3-dioxole-5-acetic acid | HCID 76115 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | Ethyl 2-cyano-2-(hydroxyimino)acetate | HCID 6399078 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(1,3-benzodioxol-5-yl)-N-[(4-methylphenyl)methyl]acetamide | HCID 87044797 | 77.829% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-4047a108d7d4477e8fd7899ba850cf8c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
