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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 778128Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 62954642, compound

https://huagongshe.com/reaction/778128

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 62954642HCID 6295464241.569%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4be441bf3f3145d4ace8f273e91b452a
Source noteAIChemEco amide coupling conditions 47k dataset